ERA4TB accelerates the development of new treatment regimens for tuberculosis.

Effects of the COVID-19 on the fight against tuberculosis

The general public is well aware of the tragic impact of the COVID-19 on the community in terms of lives, disruption of livelihoods and social distress. Far less obvious are the indirect effects that the outbreak exert on other major diseases of global incidence like tuberculosis. To contain the spread of the COVID-19, most countries have imposed strict lockdown measures that, however necessary, are negatively affecting the programs to eradicate tuberculosis at global level by hindering TB diagnosis, notifications and likely shortening the provision of drugs against the infection.

The Stop-TB Partnership has been working on a series of models to estimate the effect of the COVID-19 outbreak on the progress of TB at global scale. These models focus on three countries with a high burden of TB and distinct social settings that constitute paradigmatic cases within the spectrum of countries in which TB has a high incidence. In the worst-case scenario, the modelers estimated that a 3-month lockdown followed by a 10-month period to return to normality could lead to an additional 6.3 million cases of TB between 2020 and 2025, and an additional 1.4 million TB deaths during this time at global level. With these figures, the gains made in the fight against TB in the last five to eight years could be lost out. The study stresses that recovering the progress made in the last years will only be possible through increasing the efforts and investments in TB.

ERA4TB stands in solidarity with the additional difficulties that the present situation imposes on patients and professionals involved in treating TB. ERA4TB is committed with the development of new drugs of easy administration and effectivity against resistant strains, the consortium hopes to help mitigate the consequences of the COVID-19 outbreak on the battle against TB.

ERA4TB (European Regimen Accelerator for Tuberculosis) project is a public-private initiative devoted to accelerate the development of new treatment regimens for tuberculosis.

Objectives

The main objective of ERA4TB is to create a European open platform to accelerate the development of new regimens for the treatment of tuberculosis.

Ambition

All Member States of WHO and the UN have committed to the goal of ending the TB epidemic by 2030 through their unanimous endorsement of WHO’s End TB Strategy at the World Health Assembly and their adoption of the UN Sustainable Development Goals (SDGs).

Ambition

All Member States of WHO and the UN have committed to the goal of ending the TB epidemic by 2030 through their unanimous endorsement of WHO’s End TB Strategy at the World Health Assembly and their adoption of the UN Sustainable Development Goals (SDGs).

Structure

The ERA4TB platform is based on a progression pipeline that can cater for a variety of molecules at different stages of development.

News

Follow our articles and ERA4TB news

Event

SAVE THE DATE: ERA4TB Webinar on Challenges of tuberculosis (TB) drug development and access – clinical, regulatory and HTA perspectives

ERA4TB is launching a series of webinars aimed at exploring key topics in relation to…
Press

ERA4TB participates in the #WorldEBHCDay campaign, ‘Partnerships for Purpose’

The article ‘How partnerships are driving new treatments for tuberculosis’ has just been published on World…
Event

ERA4TB 5th Consortium Meeting: First F2F meeting in Madrid after the pandemic

On June 20th and 21st the fifth Consortium Meeting took place in Madrid. The meeting…

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A recent analysis of the effect of COVID on household Mtb transmission in West Bengal: "secondary attack rate of household TB disease transmission was 34% LOWER during the pandemic period".
https://www.sciencedirect.com/science/article/pii/S001957072200018X

🎞️We hope you are catching up on the #UnionConf recordings. Do not miss the plenary sessions and special sessions, including topics like 🎯'Preparing for the Next Pandemic' and 'It's Time to Rethink Respiratory Disease Transmission and How to Prevent It'
📌https://tinyurl.com/yph6976m

If you weren't able to join us last week, for the launch of our webinar series, you can now watch the session on 'challenges to #tuberculosis drug development and access' on Youtube: https://youtu.be/n6NxPFxHOys
The session was hosted by our partner @NICEComms
#webinar #AMR #WAAW2022

On #WorldAIDSDay, we remember all who have died from AIDS-related illnesses, and stand in solidarity with people who are affected by HIV.

TB remains the leading cause of death among those living with #HIV.

📢We must continue advocating for a world free of #HIV #AIDS and #TB.

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